Regimen Lab Skincare Encyclopedia ?

Genistein

*Preliminary Lab Notes* - Full Entry Under Development

Ingredient Profile

Common Name: Genistein
INCI: Genistein
Source: Soybeans, Fava beans
Genistein Molecule

kligman ingredient evaluation

Penetration: Under analysis
Biochemical Mechanism: Under analysis
Level of Evidence: Under analysis

Regimen's Take

Genestein is a potent antioxidant and a phytoestrogen (a biomimetic molecule). It not only acts as a free radical scavenger, but it modulates process in the skin that can prevent the destruction of elastin, collagen, and hyaluronic acid. While we love this ingredient, here’s the catch. It’s derived from a plant originally used as a dye, so when we formulate it in skincare, using too much can create a yellow a cast on the skin.

TLDR

  • potent naturally-sourced antioxidant
  • biomimetic anti-aging properties due to it’s action on estrogen receptors

The full Regimen Lab Skincare Encyclopedia Entry for Genistein is in development. Check back in a few weeks for an update!

What is Genistein?
Genistein is an isoflavone used in skincare products to improve skin dryness and wrinkles.Clinical trials
https://www.tandfonline.com/doi/full/10.1080/09513590.2017.1320708?scroll=top&needAccess=true - Collagen concentration on the facial skin of postmenopausal women after topical treatment with estradiol and genistein: a randomized double-blind controlled trial.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936027/ - Genistein aglycone improves skin repair in an incisional model of wound healing

?
The Skincare Encyclopedia aims to improve public understanding of the biology and chemistry of skincare. The Encyclopedia is rooted in core scientific principles and extensive research, in many cases in collaboration with the authors of the original studies referenced. This is a project of Regimen Lab, maintained by a group of multidisciplinary scientists, MDs, and researchers.